Don't ask me what this means -- I'm not a seismologist. Earthquakes are practically impossible to predict, as in, "there will be one of this magnitude at this time at this location." I don't know anything about the more recent seismic activity of the Carolinas ... obviously devastating earthquakes can happen, as the Charleston quake of 1886 shows. The region is moderately active with respect to seismicity, so a few minor tremors here and there are hardly unexpected. It's good to keep a perspective based on geologic time on these things! :)
[Both earthquakes made The State. However, clicking on each headline opens a blank page in both browsers that I use. Or rather, a page loads with everything on there, including the headline, but no story! Weird.]
More info on SC seismicity at the South Carolina Seismic Network at USC.